华惠动物门诊病例——肉鸡药物中毒

兽医非浅

<P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><FONT face="Times New Roman"></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><SPAN style="mso-spacerun: yes"><FONT face="Times New Roman"> </FONT></SPAN></SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><SPAN style="mso-spacerun: yes"><FONT face="Times New Roman"></FONT></SPAN></SPAN> </P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><SPAN style="mso-spacerun: yes"></SPAN></SPAN> </P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><SPAN style="mso-spacerun: yes"> </SPAN></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">主诉：2</SPAN>400</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">只肉鸡</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">13</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">天采食量</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">3</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">代</SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">从做完疫苗后，第</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">2</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">天开始用药：杨树花口服液（黄色液体估计是痢菌净）治疗大肠杆菌说明一瓶兑水</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">600</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">斤，实际用法是</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">1</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">瓶兑水</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">100</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">斤水让鸡集中喝，含泰乐菌素的药物治疗呼吸道病，还有球虫的中药拌料治疗球虫。用药第一天后出现死亡，一天死亡</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">25</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">只，大都死亡较大的鸡，大群鸡精神兴奋，尖叫，乱跑，死亡的鸡有翻肚的也有趴着的，鸡爪发干。昨天从今天死亡也有</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">20</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">多只。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><SPAN style="mso-spacerun: yes"><FONT face="Times New Roman">   </FONT></SPAN></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">剖解：</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">每只鸡都出现不同程度的肾肿胀，有的呈大理石样肿大，输尿管内有白色尿酸盐。有的肾充血呈绯红色肿大，有的输尿管内有黄色物。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN lang=EN-US><SPAN style="mso-spacerun: yes"><FONT face="Times New Roman">  </FONT></SPAN></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">腺胃有</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">3</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">只都出现腺胃壁有大小不等的出血斑块，腺胃乳头之间也有出血。有一只腺胃乳头出血严重呈绯红样出血。肌胃皱褶有不同程度的出血溃疡，鸡内金有不同程度的糜烂。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">经大群情况介绍和解剖病变，确诊为药物中毒。因药物是其他门诊给的，不清楚药物的主要成分，对那种药物中毒不好判定。怀疑治疗大肠杆菌的含有痢菌净，治疗球虫的中药可能还有磺胺类的或者是马杜拉霉素。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">治疗：</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">把所有用的药物立即停用，改用解毒，通肾药。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">用口服葡萄糖</SPAN><SPAN lang=EN-US><FONT face="Times New Roman">5%</FONT></SPAN><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">饮水配合高档多维素和ＶＣ白天饮水，晚上用通肾健肾的药物配合口服葡萄糖２％饮水。连用３天。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">第二天打电话，说晚上死亡３只，大群病情已经控制。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">提醒广大养殖朋友：</SPAN></P><P style="TEXT-INDENT: 21pt; MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">给鸡看病虽心切，用药需谨慎。２０天内的鸡，不要集中饮药，不要用毒性大的药物。</SPAN></P><P style="MARGIN: 0cm 0cm 0pt" class=MsoNormal><SPAN style="FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-hansi-font-family: 'Times New Roman'">提醒广大兽药厂家技术员和临床兽医工作者，给客户用药一定要清楚药的真实含量，谨慎下药，给客户一定要交代清楚药的用法，用量。</SPAN></P>

梅。兰。竹。菊

可以排除痢菌净！。。。。

不会飞的山鸡

中毒的滋味不好受呀，就是解好了毒，下一步用药也要注意啦

高级新手

现在的兽药说明书都是路唇不对马嘴，有些药加10倍也没事，但磺胺类加一倍就可能中毒。

佐君畜牧

确实是药物中毒，但基本可以排除痢菌净中毒。怀疑磺胺类药物中毒，不知道楼主有没有观察肌肉有没有变化，如马杜拉霉素中毒应该能看到肌肉出血和肾肿大出血、有尿酸盐沉积的现象。